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ABSTRACT
Background
Hysterectomy entails the removal of the uterus. The indications can include benign, premalignant and malignant conditions. Little is known about the clinicopathological correlation in hysterectomies, profile of indications and the prevalence of hysterectomies in South Africa. This is despite hysterectomy being the second most common gynaecological procedure. This study will report on the clinicopathological correlation in hysterectomy specimens submitted, the profile of clinical indications and histopathological diagnoses and calculate the prevalence of hysterectomies done at DGMAH.
Method
This is a retrospective descriptive study that looked at histopathology reports on hysterectomy specimens received from the Department of Obstetrics and Gynaecology at DGMAH between 2020 and 2021. Relevant data such as age, indication and histopathological diagnosis was extracted from these reports using the NHLS Trackcare system. Statistical analysis was performed using Stata software, version 7.0
Result
A total of 275 hysterectomies formed the study cohort. The mean age was 51.5 (21-83 years). The most common clinical indication and histopathological diagnosis was leiomyoma. The prevalence of hysterectomies performed at DGMAH was 12.2%. The concordance of the 5 most frequent clinical indications was calculated and found an overall percentage agreement of 84.8% and a Kappa coefficient = 0.795 (p = <0.001).
Conclusion
The Kappa value of the top five most frequent clinical indications is categorized as substantial, indicating that the diagnostic procedures used in clinical practice are most likely adequate to give accurate pre-operative diagnoses.